From the above linked article:
1 - Plug the usb cable into the usb port on your computer.This started to work on my Palm TX but is currently stopping the middle. I had this working a few months back, but don't regularly sync up. Just a quick note here so I would know where I found the original information
2 - Put your Palm in the cradle or plug in the cable.
3 - Go to System->Preferences->Palm OS Devices
4 - In the Pilot Settings pop-up select the Devices tab and click Add.
5 - In the Device Settings pop-up enter info as follows:
Name: Cradle
Port: /dev/ttyUSB0 <--*see bottom Speed: 57600 Timeout: 2 Type: USB Click OK and then click Add again and enter: Name: Cradle1 Port: /dev/ttyUSB1 <--*see bottom Speed: 57600 Timeout: 2 Type: USB 6 - Now, back in the Pilot Settings window select Pilots and click Add 7 - Once the new pop-up appears, press Synchronize on your PalmPDA While it is searching, select "Get from pilot" in the pop-up window just mentioned. Your computer should synchronize and get a Name, ID and username from your PDA. Now your device officially exists in the gpilot database on your computer. 8 - Close the most recent pop-up. You should still have the main Pilot Settings window open. Click the Conduits tab to decide what you want to synchronize and so on...this is essentially the same as what you may have used on other OS's. Finally: Every time you want to sync, make sure gpilot is running and then hit the sync button on your PDA.